Searchable abstracts of presentations at key conferences in endocrinology
ea0029p1155 | Nuclear receptors and Signal transduction | ICEECE2012
Central diabetes insipidus associated with impaired renal aquaporin-1 expression in mice lacking the oxysterol receptor liver X receptor β
We have previously shown that in pancreatic ductal epithelial cells, the expression of the water channel aquaporin-1 is under the control of the oxysterol receptor liver X receptor β. The aim of the present study was to investigate water balance in mice lacking each LXR isoform.Given free access to water, LXRβ−/− mice demonstrated an abnormal daily excretion of highly diluted urine, polyuria, with increased water intake compared to ...
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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